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Medical cannabis and cognitive performance in middle to old adults treated for chronic pain

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The Impact of Medical Cannabis on Intermittent and Chronic Opioid Users with Back Pain: How Cannabis Diminished Prescription Opioid Usage

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Britain’s financial watchdog sets out rules for cannabis listings

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Britainโ€™s markets watchdog opened the door to cannabis company listings on Friday by setting out how it would navigate laws to prevent pocketing proceeds from criminal use of the drug, reports Reuters.*

The Financial Conduct Authority set out its โ€œapproachโ€ to cannabis-related companies interested in a UK listing, pending public consultation on more formal guidance in due course.*

The legalisation of cannabis, including for recreational use in Canada and a number of U.S. states, fuelled a speculative โ€œgreen rushโ€ on Toronto and New York stock markets last year, with analysts expecting some listings in Europe in 2020.*

The FCA said that while medicinal cannabis was legalised in Britain in 2018, investment in overseas licensed medicial cannabis companies remains a legally complex area, with a risk of triggering broadly-defined British law that prevent financial gain from criminal activity.*

Proceeds from recreational cannabis companies, even when located in countries that have legalised it, are proceeds of crime under the law, it said.*

โ€œWe canโ€™t assume a person who has been licensed in an overseas country would receive a licence here in the UK as licensing regimes differ globally,โ€ the FCA said.*

โ€œUK-based medicinal cannabis companies can be admitted to the Official List, if the company has the appropriate Home Office licences for their activities where they are required,โ€ it added.*

The FCA said overseas-licensed medicinal cannabis companies and cannabis oil companies could list in Britain if the proceeds of crime law does not apply, and they meet listing criteria.*

* original article

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*** ndlr. : –.

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The pharmacokinetics, efficacy, and safety of a novel selectiveโ€dose cannabis inhaler in patients with chronic pain: A randomized, doubleโ€blinded, placeboโ€controlled trial

European Journal of Pain
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Canada’s Pascal Biosciences partners with SoRSE to test cannabis-based cancer therapy*

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Canadian biotech Pascal Biosciences Inc will start an early stage study of a cannabis-based cancer therapy in partnership with SoRSE Technology Corp, the companies told Reuters on Monday, reports Reuters.*

Seattle, Washington-based SoRSEโ€™s technology helps create water-soluble cannabidiol, a non-psychoactive chemical found in cannabis plants that is being widely used to make beverages, chocolates, lotions and other products.*

Chief Executive Officer Howard Lee said SoRSE would pay Pascal for research expenses as it tests the experimental treatment PAS-393, which the companies hope can complement the so-called checkpoint inhibitors thought to help take the brakes off the immune system in fighting cancer.*

โ€œWeโ€™ve got the drug discovery and development expertise and SoRSE has formulation capabilities and that will help get the drug into the clinic,โ€ said Pascal Chief Executive Officer Patrick Gray, adding the companies hope to begin Phase I trials over the next year.*

Gray added Pascal would be able to complete Phase-1A testing by the end of the 15-month partnership with SoRSE and may choose to continue clinical development as equal partners after that.*

The collaboration marks a push to test cannabis-based compounds in extensive clinical trials, a leap for an industry that has struggled to prove the medical benefits of marijuana-derived products.*

The U.S. Food and Drug Administration in 2018 approved the first marijuana plant-derived drug, GW Pharmaceuticals Plcโ€™s Epidiolex, to treat two severe forms of epilepsy.*

In 1985, the FDA signed off on Marinol, a medicine containing synthetic cannabis molecules, which is used to treat weight loss in AIDS patients and nausea in cancer patients on chemotherapy.*

* article original

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Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study of the Efficacy, Safety, and Tolerability of THC:CBD Extract and THC Extract in Patients with Intractable Cancer-Related Pain

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Associations between medical cannabis and prescription opioid use in chronic pain patients: A preliminary cohort study

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Utilization of medicinal cannabis for pain by individuals with spinal cord injury

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Efficacy of Inhaled Cannabis on Painful Diabetic Neuropathy

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Pakistan approves first industrial hemp production – minister

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Pakistanโ€™s government has approved the industrial production of hemp, which could generate foreign exchange of up to $1 billion in the next three years, the minister for science and technology said on Wednesday, report Reuters.*

A cabinet meeting chaired by Prime Minister Imran Khan approved a summary on Tuesday to allow legal production for the first time, the minister Fawad Chaudhry told a news conference in Islamabad.*

โ€œWe want that this hemp market could give us around $1 billion in the next three years,โ€ he said, adding the global market is worth around $25 billion.*

The summary seen by Reuters says the ministry sought permission to cultivate industrial hemp after deliberation by the ministries of commerce, narcotics control and national health services.*

Hemp seeds produce hemp oil, while the leaf is used in medicine and the stem can be turned into fibre to replace cotton in the textile industry.*

Chaudhry said the compound cannabidiol found in the hemp plant has an important role in medical science and therapies to mitigate severe and chronic pain affecting for instance cancer patients or those who have lost limbs.*

Across the world, companies have been seeking to tap into the market for medicinal cannabis.*

The minister said the cultivation of hemp – a strain of the cannabis plant that contains little or no tetrahydrocannabinol, or THC, the substance that makes people high – will only be allowed under government control and the venture should not be confused with poppy-growing.*

Pakistanโ€™s northwestern lawless districts along the Afghan border have been home to the illegal cultivation of poppies for opium and heroin and the production of cannabis, supplied to the local narcotics market or smuggled internationally.*

* original article

**image

*** ndlr. : –.